Publications

1.      Germani A., Fusco C., Martinotti S., Musarò A., Molinaro M., Zani BM. TPA-induced differentiation of human rhabdomyosarcoma cells involves dephosphorylation and nuclear accumulation of mutant p53. Biochem Biophys Res Commun. 1994, 202:17-24.

 

2.      Musarò A., Cusella De Angelis MG, Germani A., Ciccarelli C., Molinaro M., Zani BM; Enhanced expression of myogenic regulatory genes in aging skeletal muscle Exp Cell Res. 1995; 221:241-8.

 

3.      Barton-Davis ER, Shoturma DI, Musarò A, Rosenthal N, Sweeney HL. Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function. Proc Natl Acad Sci U S A. 1998 95(26):15603-7.

 

4.      Musarò A., Rosenthal N. Maturation of the myogenic program is induced by postmitotic expression of insulin-like growth factor I. Mol Cell Biol. 1999 19:3115-24.

 

5.      Musarò A., Rosenthal N. Transgenic mouse models of muscle aging. Exp Gerontol. 1999; 34(2):147-56. Review.

 

6.      Musarò A, McCullagh KJ, Naya FJ, Olson EN, Rosenthal N. IGF-1 induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATc1. Nature. 1999; 400: 581-5.

 

7.      Tsao L, Neville G, Musarò A, McCullagh KJ, Rosenthal N. Revisiting calcineurin and  human heart failure. Nature Medicine 2000; 6: 2-3.

 

8.      Musarò A, McCullagh K, Paul A, Houghton L, Dobrowolny G, Molinaro M, Barton ER, Sweeney HL, Rosenthal N. Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle. Nature Genetics 2001; 27: 195-200.

 

9.      Barton ER, Morris L., Musaro A., Rosenthal N., and Sweeney H.L. Muscle specific expression of Insulin-like Growth Factor I counters muscle decline in mdx mice. J.Cell Biol. 2002; 157: 137-147.

 

10.    Scicchitano BM, Spath L, Musarò A, Molinaro M, Adamo S, and Nervi C. The Myocyte Enhancer Factor 2 is Essential for Myogenin Expression during AVP Induced Myogenesis. J. Endocrinology 2002; 16: 1407-16.

 

11.    Musarò A. and Rosenthal N. The role of local Insulin-like Growth Factor-1 isoforms in the pathophysiology of skeletal muscle. Current Genomics 2002; 3: 149-162.

 

12.    Rosenthal, N, Musarò A. Gene therapy for cardiac cachexia? International Journal of Cardiology 2002 85: 185-191

 

13.    Winn N., Paul A., Musarò A., Rosenthal N. Insulin-like Growth Factor isoforms in skeletal muscle aging, regeneration and disease. Cold Spring Harbor Symposia on Quantitative Biology. 2002; LXVII: 507-518.

 

14.    Musarò A, Rosenthal N. Attenuating muscle wasting: cell and gene therapy approaches. Current Genomics 2003; 4:575-585.

 

15.    Bertini E, Biancalana V, Bolino A, Buj Bello A, Clague M, Guicheney P, Jungbluth H, Kress W, Musarò A, Nandurkar H, Pirola L, Romero N, Senderek J, Suter U, Sewry C, Tronchere H, Wallgren-Pettersson C, Wishart MJ, Laporte J. 118th ENMC International Workshop on Advances in Myotubular Myopathy. 26-28 September 2003, Naarden, The Netherlands. (5th Workshop of the International Consortium on Myotubular Myopathy). Neuromuscul Disord. 2004 14:387-96.

 

16.    Musarò A, Giacinti C, Borsellino G, Dobrowolny G, Pelosi L, Cairns L, Ottolenghi S, Bernardi G, Cossu G, Battistini L, Molinaro M, Rosenthal N. Muscle restricted expression of mIGF-1 enhances the recruitment of stem cells during muscle regeneration. Proc Natl Acad Sci U S A 2004; 101: 1206-1210.

 

17.    Dobrowolny G, Giacinti C, Pelosi L, Nicoletti C, Winn N, Barberi L, Molinaro M, Rosenthal N, Musarò A. Muscle expression of a local Igf-1 isoform protects motor neurons in an ALS mouse model. J Cell Biol. 2005;168:193-9.

 

18.    Scicchitano BM, Spath L, Musarò A, Molinaro M, Rosenthal N, Nervi C, Adamo S. Vasopressin-dependent Myogenic Cell Differentiation Is Mediated by Both Ca2+/Calmodulin-dependent Kinase and Calcineurin Pathways. Mol Biol Cell. 2005; 16:3632-41.

 

19.    Musarò A. Growth factor enhancement of muscle regeneration: a central role of IGF-1. Arch Ital Biol. 2005;143:243-8

 

20.    Denti MA, Rosa A, D'Antona G, Sthandier O, De Angelis FG, Nicoletti C, Allocca M, Pansarasa O, Parente V, Musarò A, Auricchio A, Bottinelli R, Bozzoni I. Body-wide gene therapy of Duchenne muscular dystrophy in the mdx mouse model. Proc Natl Acad Sci U S A. 2006; 103:3758-63.

 

21.    Denti MA, Rosa A, D'Antona G, Sthandier O, Angelis FG, Nicoletti C, Allocca M, Pansarasa O, Parente V, Musaro A, Auricchio A, Bottinelli R, Bozzoni I. Chimeric Adeno-Associated Virus/Antisense U1 Small Nuclear RNA Effectively Rescues Dystrophin Synthesis and Muscle Function by Local Treatment of mdx Mice. Human Gene Ther. 2006 17: 1-10.

 

22.    Musarò A., Dobrowolny G., Rosenthal N. The neuroprotective effects of a locally acting IGF-1 isoform. Experimental Gerontology 2007; 42:76-80.

 

23.    Rosenthal N, Santini MP, Musaro A. Growth factor enhancement of cardiac regeneration. Cell Transplant. 2006;15 Suppl 1:S41-5.

 

24.    Musarò A., Rosenthal N. The critical role of Insulin-like Growth Factor-1 isoforms in the physiopathology of skeletal muscle. Current Genomics 2006; 3: 19-32.

 

25.    Pelosi L, Giacinti C, Nardis C, Borsellino G, Rizzuto E, Nicoletti C, Wannenes F, Battistini L, Rosenthal N, Molinaro M, Musarò A. Local expression of IGF-1 accelerates muscle regeneration by rapidly modulating inflammatory cytokines and chemokines. FASEB J. 2007; 21:1393-402.

 

26.    Musarò A., Giacinti C., Pelosi L., Dobrowolny G., Barberi L., Nardis C., Coletti D., Scicchitano B.M., Adamo S., Molinaro M.. Stem Cell-mediated muscle regeneration and repair in aging and neuromuscular diseases. European Journal of Histochemistry. 2007; 51 Suppl 1:35-43.

 

27.    Fanzani A, Musarò A, Stoppani E, Giuliani R, Colombo F, Preti A, Marchesini S. Hypertrophy and atrophy inversely regulate Caveolin-3 expression in myoblasts. Biochem Biophys Res Commun. 2007; 357:314-8.

 

28.    Pelosi M, Marampon F, Zani BM, Prudente S, Perlas E, Caputo V, Cianetti L, Berno V, Narumiya S, Kang SW, Musarò A, Rosenthal N. ROCK2 and its alternatively spliced isoform ROCK2m positively control the maturation of the myogenic program. Mol Cell Biol. 2007; 27:6163-76.

 

29.    Dobrowolny G, Aucello M, Molinaro M, Musarò A. Local expression of mIgf-1 modulates ubiquitin, caspase and CDK5 expression in skeletal muscle of an ALS mouse model. Neurol Res. 2008; 30:131-6.

 

30.    Del Prete Z, Musarò A, Rizzuto E. Measuring Mechanical Properties, Including Isotonic Fatigue, of Fast and Slow MLC/mIgf-1 Transgenic Skeletal Muscle. Ann Biomed Eng. 2008; 36:1281-90.

 

31.    Denti M A, Incitti T, Sthandier O, Nicoletti C, De Angelis F, Rizzuto E, Auricchio A, Musarò A, Bozzoni I. Long-term benefit of AAV/antisense-mediated exon skipping in dystrophic mice. Human Gene Therap. 2008; 19:601-8.

 

32.    Giacinti C, Musarò A, De Falco G, Jourdan I, Molinaro M, Bagella L, Simone C, Giordano A. Cdk9-55: A new player in muscle regeneration. J Cell Physiol. 2008; 216:576-82.

 

33.    Dobrowolny G, Aucello M, Rizzuto E, Beccafico S, Mammucari C, Bonconpagni S, Belia S, Wannenes, F Nicoletti, C Del Prete Z, Rosenthal N, Molinaro M, Protasi F, Fanò G, Sandri M, and Musarò A. Skeletal muscle is a primary target of SOD1G93A -mediated toxicity Cell Metabolism 2008; 8:425-36.

 

34.    Aucello M, Dobrowolny G, Musarò A. Localized accumulation of oxidative stress causes muscle atrophy through activation of an autophagic pathway. Autophagy. 2009; 5:527-9.

 

35.    Palazzolo I., Stack C., Kong L., Musaro A., Adachi H., Katsuno M., Sobue G., Taylor J.P., Sumner C., Fischbeck K., and Pennuto M. Overexpression of IGF-1 in Muscle Attenuates Disease in a Mouse Model of Spinal and Bulbar Muscular Atrophy. Neuron 2009; 63:316-28.

 

36.    Rizzuto E, Musarò A, Catizone A, Del Prete Z. Measuring tendon properties in mdx mice: Cell viability and viscoelastic characteristics. J. Biomech. 2009; 42:2243-8.

 

37.    Colombini B, Benelli G, Nocella M, Musarò A, Cecchi G, Bagni MA. Mechanical properties of intact single fibres from wild-type and MLC/mIgf-1 transgenic mouse muscle. J Muscle Res Cell Motil. 2009;30:199-207.

 

38.    Scicchitano BM, Rizzuto E, and Musarò A. Counteracting muscle wasting in aging and neuromuscular diseases: the critical role of IGF1. Aging 2009; 1: 451-457.

 

39.    Messina S, Bitto A, Aguennouz M, Mazzeo A, Migliorato A, Polito F, Irrera N, Altavilla D, Vita GL, Russo M, Naro A, De Pasquale MG, Rizzuto E, Musarò A, Squadrito F, Vita G. Flavocoxid counteracts muscle necrosis and improves functional properties in mdx mice: a comparison study with methylprednisolone. Exp Neurol. 2009; 220:349-58.

 

40.    Musarò A, Fulle S and Fanò G. Oxidative stress and muscle homeostasis. Curr Opin Clin Nutr Metab Care 2010; 13:236-42.

 

41.    Melchionna R, Di Carlo A, De Mori R, Cappuzzello C, Barberi L, Musarò A, Cencioni C, Fujii N, Tamamura H, Crescenzi M, Capogrossi MC, Napolitano M, Germani A. Induction of myogenic differentiation by SDF-1 via CXCR4 and CXCR7 receptors. Muscle Nerve. 2010; 41:828-35.

 

42.    Musaro A. Comments on Point:Counterpoint: IGF is/is not the major physiological regulator of muscle mass. The strange case of IGF-1. J Appl Physiol. 2010; 108:1826.

 

43.    Cacchiarelli D, Martone J, Girardi E, Cesana M, Incitti T, Morlando M, Nicoletti C, Santini T, Sthandier O, Barberi L, Auricchio A, Musarò A, Bozzoni I. MicroRNAs involved in molecular circuitries relevant for the Duchenne muscular dystrophy pathogenesis are controlled by the dystrophin/nNOS pathway. Cell Metab. 2010; 12:341-51.

 

44.    Vinciguerra M, Musaro A, Rosenthal N. Regulation of muscle atrophy in aging and disease. Adv Exp Med Biol. 2010; 694:211-33.

 

45.    Musarò A. State of the art and the dark side of amyotrophic lateral sclerosis World J Biol Chem. 2010; 1: 62-68.

 

46.    Bosch-Marcé M, Wee CD, Martinez TL, Lipkes CE, Choe DW, Kong L, Vanmeerbeke JP, Musarò A, Sumner CJ. Increased IGF-1 in muscle modulates the phenotype of severe SMA mice. Hum Mol Genet. 2011 20:1844-53.

 

47.    Carosio S, Berardinelli MG, Aucello M, Musarò A. Impact of ageing on muscle cell regeneration. Ageing Res Rev. 2011;10:35-42.

 

48.    Dobrowolny G, Aucello M, Musarò A. Muscle atrophy induced by SOD1G93A expression does not involve the activation of caspase in the absence of denervation. Skelet Muscle. 2011;1(1):3.

 

49.    Toschi A, Severi A, Coletti D, Catizone A, Musarò A, Molinaro M, Nervi C, Adamo S, Scicchitano BM. Skeletal muscle regeneration in mice is stimulated by local overexpression of v1a-vasopressin receptor. Mol Endocrinol. 2011; 25:1661-73.

 

50.    Kuraitis D, Zhang P, Zhang Y, Padavan DT, McEwan K, Sofrenovic T, McKee D, Zhang J, Griffith M, Cao X, Musarò A, Ruel M, Suuronen EJ. A stromal cell-derived factor-1 releasing matrix enhances the progenitor cell response and blood vessel growth in ischaemic skeletal muscle. Eur Cell Mater. 2011; 22:109-23.

 

51.    Forte G, Pietronave S, Nardone G, Zamperone A, Magnani E, Pagliari S, Pagliari F, Giacinti C, Nicoletti C, Musaró A, Rinaldi M, Ribezzo M, Comoglio C, Traversa E, Okano T, Minieri M, Prat M, Di Nardo P. Human cardiac progenitor cell grafts as unrestricted source of supernumerary cardiac cells in healthy murine hearts. Stem Cells. 2011;29:2051-61.

 

52.    Kern H, Pelosi L, Coletto L, Musarò A, Sandri M, Vogelauer M, Trimmel L, Cvecka J, Hamar D, Kovarik J, Löfler S, Sarabon N, Protasi F, Adami N, Biral D, Zampieri S, Carraro U. Atrophy/hypertrophy cell signaling in muscles of young athletes trained with vibrational-proprioceptive stimulation. Neurol Res. 2011;33:998-1009.

 

53.    Kuraitis D, Giordano C, Ruel M, Musarò A, Suuronen EJ. Exploiting extracellular matrix-stem cell interactions: A review of natural materials for therapeutic muscle regeneration. Biomaterials. 2012; 33:428-43.

 

54.    Sandonà D, Desaphy JF, Camerino GM, Bianchini E, Ciciliot S, Danieli-Betto D, Dobrowolny G, Furlan S, Germinario E, Goto K, Gutsmann M, Kawano F, Nakai N, Ohira T, Ohno Y, Picard A, Salanova M, Schiffl G, Blottner D, Musarò A, Ohira Y, Betto R, Conte D, Schiaffino S. Adaptation of Mouse Skeletal Muscle to Long-Term Microgravity in the MDS Mission. PLoS One. 2012; 7:e33232.

 

55.    Nucera E, Nicoletti C, Chiapparino C, Pacello ML, D'Alessio V, Musarò A, De Santis R. AvidinOX for tissue targeted delivery of biotinylated cells. Int J Immunopathol Pharmacol. 2012; 25:239-46.

 

56.    Murdocca M, Malgieri A, Luchetti A, Saieva L, Dobrowolny G, De Leonibus E, Filareto A, Quitadamo MC, Novelli G, Musarò A, Sangiuolo F. IPLEX administration improves motor neuron survival and ameliorates motor functions in a severe mouse model of SMA. Mol Med. 2012 Sep 25;18:1076-85.

 

57.    Musarò A. To the heart of the problem. mIGF-1: local effort for global impact. Aging (Albany NY). 2012; 4:377-8.

 

58.    Klionsky et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2012; 8:445-544.

 

59.    Kuraitis D, Ebadi D, Zhang P, Rizzuto E, Vulesevic B, Padavan DT, Al Madhoun A, McEwan KA, Sofrenovic T, Nicholson K, Whitman SC, Mesana TG, Skerjanc IS, Musarò A, Ruel M, Suuronen EJ. Injected matrix stimulates myogenesis and regeneration of mouse skeletal muscle after ischaemic injury. Eur Cell Mater. 2012; 24:175-95

 

60.    Rizzuto E, Catizone A, Musarò A, Del Prete Z. Dystrophic tendon functionality is recovered by muscle-specific expression of insulin-like growth factor in mdx mice. J Biomech. 2013; 46:604-7

 

61.    Musarò A. Understanding ALS: new therapeutic approaches. FEBS J. 2013; 280:4315-22.

 

62.    Kuraitis D, Berardinelli MG, Suuronen EJ, Musarò A. A Necrotic Stimulus is Required to Maximize Matrix-Mediated Myogenesis. Dis Model Mech. 2013; 6:793-801

 

63.    Carosio S, Barberi L, Rizzuto E, Nicoletti C, Prete ZD, Musarò A. Generation of eX vivo-vascularized Muscle Engineered Tissue (X-MET). Sci Rep. 2013; 3:1420.

 

64.    Bucci L, Yani SL, Fabbri C, Bijlsma AY, Maier AB, Meskers CG, Narici MV, Jones DA, McPhee JS, Seppet E, Gapeyeva H, Pääsuke M, Sipilä S, Kovanen V, Stenroth L, Musarò A, Hogrel JY, Barnouin Y, Butler-Browne G, Capri M, Franceschi C, Salvioli S. Circulating levels of adipokines and IGF-1 are associated with skeletal muscle strength of young and old healthy subjects. Biogerontology. 2013; 14:261-72.

 

65.    Barberi L, Scicchitano BM, De Rossi M, Bigot A, Duguez S, Wielgosik A, Stewart C, McPhee J, Conte M, Narici M, Franceschi C, Mouly V, Butler-Browne G, Musarò A. Age-dependent alteration in muscle regeneration: the critical role of tissue niche. Biogerontology. 2013; 14:273-92

 

66.    Sandri M, Barberi L, Bijlsma AY, Blaauw B, Dyar KA, Milan G, Mammucari C, Meskers CG, Pallafacchina G, Paoli A, Pion D, Roceri M, Romanello V, Serrano AL, Toniolo L, Larsson L, Maier AB, Muñoz-Cánoves P, Musarò A, Pende M, Reggiani C, Rizzuto R, Schiaffino S. Signalling pathways regulating muscle mass in ageing skeletal muscle. The role of the IGF1-Akt-mTOR-FoxO pathway. Biogerontology. 2013;14:303-23.

 

67.    Pierno S, Camerino GM, Cannone M, Liantonio A, De Bellis M, Digennaro C, Gramegna G, De Luca A, Germinario E, Danieli-Betto D, Betto R, Dobrowolny G, Rizzuto E, Musarò A, Desaphy JF, Camerino DC. Paracrine Effects of IGF-1 Overexpression on the Functional Decline Due to Skeletal Muscle Disuse: Molecular and Functional Evaluation in Hindlimb Unloaded MLC/mIgf-1 Transgenic Mice. PLoS One. 2013; 8:e65167.

 

68.    Conte M, Vasuri F, Trisolino G, Bellavista E, Santoro A, Degiovanni A, Martucci E, D'Errico-Grigioni A, Caporossi D, Capri M, Maier AB, Seynnes O, Barberi L, Musarò A, Narici MV, Franceschi C, Salvioli S. Increased Plin2 expression in human skeletal muscle is associated with sarcopenia and muscle weakness. PLoS One. 2013; 8:e73709.

 

69.    Simonatto M, Marullo F, Chiacchiera F, Musaró A, Wang JY, Latella L, Puri PL. DNA damage-activated ABL-MyoD signaling contributes to DNA repair in skeletal myoblasts. Cell Death Differ. 2013; 20:1664-74.

 

70.    Mosole S, Carraro U, Kern H, Loefler S, Fruhmann H, Vogelauer M, Burggraf S, Mayr W, Krenn M, Paternostro-Sluga T, Hamar D, Cvecka J, Sedliak M, Tirpakova V, Sarabon N, Musarò A, Sandri M, Protasi F, Nori A, Pond A, Zampieri S. Long-term high-level exercise promotes muscle reinnervation with age. J Neuropathol Exp Neurol. 2014; 73:284-94.

 

71.    Soares RJ, Cagnin S, Chemello F, Silvestrin M, Musaro A, De Pitta C, Lanfranchi G, Sandri M. Involvement of miRNAs in the Regulation of Muscle Wasting during Catabolic Conditions. J Biol Chem. 2014; 289:21909-25.

 

72.    Pelosi M, De Rossi M, Barberi L, Musarò A. IL-6 Impairs Myogenic Differentiation by Downmodulation of p90RSK/eEF2 and mTOR/p70S6K Axes, without Affecting AKT Activity. Biomed Res Int. 2014; 2014:206026.

 

73.    Kern H, Barberi L, Löfler S, Sbardella S, Burggraf S, Fruhmann H, Carraro U, Mosole S, Sarabon N, Vogelauer M, Mayr W, Krenn M, Cvecka J, Romanello V, Pietrangelo L, Protasi F, Sandri M, Zampieri S, Musarò A. Electrical stimulation counteracts muscle decline in seniors. Front Aging Neurosci. 2014; 6:189

 

74.    Guarnieri S, Morabito C, Belia S, Barberi L, Musarò A, Fanò-Illic G, Mariggiò MA. New Insights into the Relationship between mIGF-1-Induced Hypertrophy and Ca2+ Handling in Differentiated Satellite Cells. PLoS One. 2014;9:e107753.

 

75.    Zampieri S1, Pietrangelo L, Loefler S, Fruhmann H, Vogelauer M, Burggraf S, Pond A, Grim-Stieger M, Cvecka J, Sedliak M, Tirpáková V, Mayr W, Sarabon N, Rossini K, Barberi L, De Rossi M, Romanello V, Boncompagni S, Musarò A, Sandri M, Protasi F, Carraro U, Kern H. Lifelong Physical Exercise Delays Age-Associated Skeletal Muscle Decline. J Gerontol A Biol Sci Med Sci. 2015; 70:163-73.

 

76.    Biferi MG, Nicoletti C, Falcone G, Puggioni EM, Passaro N, Mazzola A, Pajalunga D, Zaccagnini G, Rizzuto E, Auricchio A, Zentilin L, De Luca G, Giacca M, Martelli F, Musio A, Musarò A, Crescenzi M. Proliferation of Multiple Cell Types in the Skeletal Muscle Tissue Elicited by Acute p21 Suppression. Mol Ther. 2015; 23:885-95.

 

77.    Rizzuto E, Pisu S, Musarò A, Del Prete Z. Measuring Neuromuscular Junction Functionality in the SOD1G93A Animal Model of Amyotrophic Lateral Sclerosis. Ann Biomed Eng. 2015; 43: 2196-206.

 

78.    Christoffolete MA, Silva WJ, Ramos GV, Bento MR, Costa MO, Ribeiro MO, Okamoto MM, Lohmann TH, Machado UF, Musarò A, Moriscot AS. Muscle IGF-1-Induced Skeletal Muscle Hypertrophy Evokes Higher Insulin Sensitivity and Carbohydrate Use as Preferential Energy Substrate. Biomed Res Int. 2015; 2015:282984.

 

79.    Cefalù S, Lena AM, Vojtesek B, Musarò A, Rossi A, Melino G, Candi E. TAp63gamma is required for the late stages of myogenesis. Cell Cycle. 2015; 14:894-901.

 

80.    Tonkin J, Temmerman L, Sampson RD, Gallego-Colon E, Barberi L, Bilbao D, Schneider MD, Musarò A, Rosenthal N. Monocyte/Macrophage-derived IGF-1 Orchestrates Murine Skeletal Muscle Regeneration and Modulates Autocrine Polarization. Mol Ther. 2015; 23:1189-200.

 

81.    Pelosi L, Coggi A, Forcina L, Musarò A. MicroRNAs modulated by local mIGF-1 expression in mdx dystrophic mice. Front Aging Neurosci. 2015; 7:69.

 

82.    Pelosi, L., Berardinelli MG, De Pasquale L, Nicoletti C, D'Amico A, Carvello F, Moneta GM, Catizone A, Bertini E, De Benedetti F, Musarò A. Functional and Morphological Improvement of Dystrophic Muscle by Interleukin 6 Receptor Blockade, EBioMedicine 2015; 2:285-93

 

83.    Pelosi L, Berardinelli MG, Forcina L, Spelta E, Rizzuto E, Nicoletti C, Camilli C, Testa E, Catizone A, De Benedetti F, Musarò A. Increased levels of interleukin-6 exacerbate the dystrophic phenotype in mdx mice. Hum Mol Genet. 2015; 24:6041-53

 

84.    Scicchitano BM, Faraldi M, Musarò A. The Proteolytic Systems of Muscle Wasting. Recent Adv DNA Gene Seq. 2015; 9:26-35.

 

85.    Pelosi M, Alfò M, Martella F, Pappalardo E, Musarò A. Finite mixture clustering of human tissues with different levels of IGF-1 splice variants mRNA transcripts. BMC Bioinformatics. 2015; 16:289.

 

86.    Oltolina F, Zamperone A, Colangelo D, Gregoletto L, Reano S, Pietronave S, Merlin S, Talmon M, Novelli E, Diena M, Nicoletti C, Musarò A, Filigheddu N, Follenzi A, Prat M. Human Cardiac Progenitor Spheroids Exhibit Enhanced Engraftment Potential. PLoS One. 2015; 10:e0137999.

 

87.    Pagliarini V, Pelosi L, Bustamante MB, Nobili A, Berardinelli MG, D'Amelio M, Musarò A, Sette C. SAM68 is a physiological regulator of SMN2 splicing in spinal muscular atrophy. J Cell Biol. 2015; 211:77-90.

 

88.    Martini M, Dobrowolny G, Aucello M, Musarò A. Postmitotic Expression of SOD1 (G93A) Gene Affects the Identity of Myogenic Cells and Inhibits Myoblasts Differentiation. Mediators Inflamm. 2015; 2015:537-853.

 

89.    Dobrowolny G, Bernardini C, Martini M, Baranzini M, Barba M and Musarò A. Muscle Expression of SOD1G93A Modulates microRNA and mRNA Transcription Pattern Associated with the Myelination Process in the Spinal Cord of Transgenic Mice. Front. Cell. Neurosci. 2015; 9:463.

 

90.    Barberi L, Scicchitano BM, Musaro A. Molecular and Cellular Mechanisms of Muscle Aging and Sarcopenia and Effects of Electrical Stimulation in Seniors. Eur J Transl Myol. 2015; 25:231-6.

 

91.    Rizzuto E, Carosio S, Faraldi M, Pisu S, Musarò A, Del Prete Z. A DIC Based Technique to Measure the Contraction of a Skeletal Muscle Engineered Tissue. Appl Bionics Biomech. 2016; 2016:7465095.

 

92.    Bacurau AV, Jannig PR, de Moraes WM, Cunha TF, Medeiros A, Barberi L, Coelho MA, Bacurau RF, Ugrinowitsch C, Musarò A, Brum PC. Akt/mTOR pathway contributes to skeletal muscle anti-atrophic effect of aerobic exercise training in heart failure mice. Int J Cardiol. 2016; 214:137-147.

 

93.    Beqollari D, Romberg CF, Dobrowolny G, Martini M, Voss AA, Musarò A, Bannister RA. Progressive impairment of CaV1.1 function in the skeletal muscle of mice expressing a mutant type 1 Cu/Zn superoxide dismutase (G93A) linked to amyotrophic lateral sclerosis. Skelet Muscle. 2016; 6:24.

 

94.    Onorato I, D'Alessandro G, Di Castro MA, Renzi M, Dobrowolny G, Musarò A, Salvetti M, Limatola C, Crisanti A, Grassi F. Noise Enhances Action Potential Generation in Mouse Sensory Neurons via Stochastic Resonance. PLoS One. 2016; 11:e0160950.

 

95.    Baruffaldi F, Montarras D, Basile V, De Feo L, Badodi S, Ganassi M, Battini R, Nicoletti C, Imbriano C, Musarò A, Molinari S. Dynamic Phosphorylation of the MEF2Cα1 Splice Variant Promotes Skeletal Muscle Regeneration and Hypertrophy. Stem Cells. 2016 Sep 10. doi: 10.1002/stem.2495.

 

96.    Zampieri S, Mammucari C, Romanello V, Barberi L, Pietrangelo L, Fusella A, Mosole S, Gherardi G, Höfer C, Löfler S, Sarabon N, Cvecka J, Krenn M, Carraro U, Kern H, Protasi F, Musarò A, Sandri M, Rizzuto R. Physical exercise in aging human skeletal muscle increases mitochondrial calcium uniporter expression levels and affects mitochondria dynamics. Physiol Rep. 2016; 4: e13005.

 

97.    Scicchitano BM, Sica G, Musarò A. Stem Cells and Tissue Niche: Two Faces of the Same Coin of Muscle Regeneration. Eur J Transl Myol. 2016; 26:6125.

 

98.    Coste CA, Mayr W, Bijak M, Musarò A, Carraro U. FES in Europe and Beyond: Current Translational Research. Eur J Transl Myol. 2016; 26(4):6369.

 

99.    Marrocco V, Fiore P, Benedetti A, Pisu S, Rizzuto E, Musarò A, Madaro L, Lozanoska-Ochser B, Bouché M. Pharmacological Inhibition of PKCθ Counteracts Muscle Disease in a Mouse Model of Duchenne Muscular Dystrophy. EBioMedicine. 2017: S2352-3964(17)30001-4.

 

100. Giusto M, Barberi L, Di Sario F, Rizzuto E, Nicoletti C, Ascenzi F, Renzi A, Caporaso N, D'Argenio G, Gaudio E, Musarò A, Merli M. Skeletal muscle myopenia in mice model of bile duct ligation and carbon tetrachloride-induced liver cirrhosis. Physiol Rep. 2017

 

101. Petrillo S, Pelosi L, Piemonte F, Travaglini L, Forcina L, Catteruccia M, Petrini S, Verardo M, D'Amico A, Musarò A, Bertini E. Oxidative stress in Duchenne muscular dystrophy: focus on the NRF2 redox pathway. Hum Mol Genet. 2017 May 3. doi: 10.1093/hmg/ddx173.

 

102. Rizzuto E, Pisu S, Nicoletti C, Del Prete Z, Musarò A. Measuring Neuromuscular Junction Functionality. J Vis Exp. 2017 Aug 6;(126). doi: 10.3791/55227.

 

103. Pelosi L, Forcina L, Nicoletti C, Scicchitano BM, Musarò A. Increased Circulating Levels of Interleukin-6 Induce Perturbation in Redox-Regulated Signaling Cascades in Muscle of Dystrophic Mice. Oxid Med Cell Longev. 2017; 2017:1987218. doi: 10.1155/2017/1987218.

 

104. Scicchitano BM, Pelosi L, Sica G, Musarò A. The physiopathologic role of oxidative stress in skeletal muscle. Mech Ageing Dev. 2017 Aug 26. pii: S0047-6374(17)30058-1. doi: 10.1016/j.mad.2017.08.009.

 

105. Dobrowolny G, Martini M, Scicchitano BM, Romanello V, Boncompagni S, Nicoletti C, Pietrangelo L, De Panfilis S, Catizone A, Bouchè M, Sandri M, Rudolf R, Protasi F, Musarò A. Muscle Expression of SOD1G93A Triggers the Dismantlement of Neuromuscular Junction via PKC-Theta. Antioxid Redox Signal. 2017 Oct 30. doi: 10.1089/ars.2017.7054

 

106. Molinari F, Pin F, Gorini S, Chiandotto S, Pontecorvo L, Penna F, Rizzuto E, Pisu S, Musarò A, Costelli P, Rosano G, Ferraro E. The mitochondrial metabolic reprogramming agent trimetazidine as an 'exercise mimetic' in cachectic C26-bearing mice. J Cachexia Sarcopenia Muscle. 2017; 8(6):954-973. doi: 10.1002/jcsm.12226.